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ACE SuperC18 Clounm
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Product Name:
ACE SuperC18 Clounm
Product Model:
Product exhibitors:
ACE/HICHROM
Brief:
Exploit selectivity at low, intermediate and high pH
Use with LC/MS compatible buffers between pH 1.5 – 11.5
High efficiency 2μm, 3μm, 5μm and 10μm particles for UHPLC and HPLC
ACE SuperC18 ClounmDetailed description of
Encapsulated Bonding Technology (EBT™) for improved chromatography and stability
The unique Encapsulated Bonding Technology (EBT™) developed for ACE SuperC18 columns dramatically increases ligand coverage of the silica surface and effectively eliminates the effect of unbonded silanol groups from separations.
This higher ligand coverage results in improved inertness, chromatographic performance and stability.
Under aggressive acidic conditions (see Figure 1) ACE SuperC18 is highly resistant to ligand cleavage, due to a combination of the Encapsulated Bonding Technology (EBT™) and ultra-inert ACE silica. Many C18 bonded columns will exhibit ligand cleavage under acidic conditions, resulting in retention shifts and/or increased peak tailing.
Under basic conditions with LC/MS compatible mobile phases, the Encapsulated Bonding Technology (EBT™) shields the ACE SuperC18 surface from dissolution whilst maintaining excellent chromatographic performance.
Traditional C18 bonded silica columns are prone to silica dissolution under such aggressive conditions, which can result in premature column deterioration.
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