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IonOpticks Aurora Frontier XT C18 column 60cmx75μm 1.7 μm

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If you are interested in this product, you can Product Name: IonOpticks Aurora Frontier XT C18 column 60cmx75μm 1.7 μm
Product Model: AUR4-60075C18
Product exhibitors: IonOpticks
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IonOpticks Aurora Frontier XT C18 column 60cmx75μm 1.7 μmDetailed description of

Product Overview

The IonOpticks Aurora column (AUR4-60075C18-XT) is a 60 cm × 75 μm nanoflow UHPLC column packed with 1.7 μm C18 (120 Å) particles. It is the first column capable of near‑total proteome coverage. Fully compatible with UHPLC systems (>1700 bar).

Key Specifications

  • Dimensions: 60 cm × 75 μm ID
  • Phase: Reversed‑phase C18, 1.7 μm, 120 Å
  • Max pressure: >1700 bar | Max temp: 60°C
  • Flow rate: 100–300 nL/min | Gradient: 90–180 min
  • Samples/day: 5–15 | Max load: 1 μg per gradient hour
  • Ion sources: EASY‑Spray, Nanospray Flex, Newomics UniESI/DuoESI
  • Packaging: 1 column/pack | Origin: Australia

Why Choose This Column?

1. Unmatched proteome coverage – Peak widths: 3.0 s (30 min) / 5.5 s (60 min). Single injection identifies >10,000 HeLa proteins.

2. Zero dead volume – Integrated packed emitter (no post‑column dead volume) + nanoZero® fitting (zero pre‑column dead volume) eliminates band broadening.

3. Built‑in HeatSync™ – Precise column temperature control ensures highly reproducible retention times across hundreds of injections.

4. Exceptional robustness – Maintains performance over >600 consecutive injections, ideal for large cohort studies.

5. Plug‑and‑play – No tools required; hand‑tighten the nanoViper fitting for instant zero‑dead‑volume connection.

Typical Applications

  • Ultra‑deep proteomics – 90–180 min gradients, >10,000 proteins/shot.
  • PTM analysis – High peak capacity separates low‑abundance modified peptides.
  • Single‑cell proteomics – Excellent performance at low‑nanogram loading.
  • Large‑scale cohort screening – Stable over hundreds of injections.
  • Biopharmaceutical characterization – Peptide mapping of mAbs and subunits.

Maintenance

  • Installation: Slide column into source, hand‑tighten 10‑32 fitting.
  • Flushing: After each run, flush with 90% ACN/H₂O at 100–300 nL/min for 15–30 min.
  • Storage: Seal ends and store in pure ACN or MeOH at 2–8°C.
  • Starter pack: AUR4-60075C18-XT-STPK (2 columns + HeatSync™ heater + controller + housing).

Series Comparison

  • Aurora Frontier XT (this) – 60 cm × 75 μm, HeatSync™, >1,700 bar, deepest coverage.
  • Aurora Ultimate XT – 25 cm × 75/150 μm, balanced resolution & throughput.
  • Aurora Elite – 15 cm × 75/150 μm, fast analysis.
  • Aurora Rapid – 8 cm × 75/150 μm, ultra‑fast separations.
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